Current Issue • December 2018 • Vol. 66

Correspondence

Creatinine Based Equations for Routine Estimation of GFR

Beuy Joob1, Viroj Wiwanitkit2

1Sanitation 1 Medical Academic Center, Bangkok, Thailand; 2Visiting professor, Hainan Medical University, China

Sir,

Dear Editor, the report on “Creatinine based equations for routine estimation of GFR” is very interesting.1 Noted that “CKD-EPI equation based on creatinine estimation is widely accepted method and clinicians may use this equation in routine clinical practice to assess kidney function among patients with type 2 diabetes.”1 Indeed, the studied equation for estimation of GFR are widely used in clinical settings. The good agreement between MDRD and CKD-EPI might imply that using any equation can provide in comparable result. A more complex calculation in CKD-EPI should be further discussed. This might be a difficult thing that some physicians might not use CKD-EPI. Nevertheless, an important concern is on the serum creatinine value. If there is any error in determination of serum creatinine, a more error in GFR value can be expected in case of using CKD-EPI (due to more parts with creatinine value in an equation for calculation). In addition, the race can affect the use of CKD-EPI. Finding a race specific equation is needed. For example, in a recent report, it was approved that CKD-EPI Pakistan’ Equation was better than classical CKD-EPI for estimation GFR of patients in Pakistan.2

References

1. Kumpatla S, Soni A, Viswanathan V. Comparison of Two Creatinine Based Equations for Routine Estimation of GFR in a Speciality Clinic for Diabetes. J Assoc Physicians India 2017; 65:38–41.
2. Ahmed S, Jafri L, Khan AH. Evaluation of ‘CKD-EPI Pakistan’ Equation for estimated Glomerular Filtration Rate (eGFR): AComparison of eGFR Prediction Equations in Pakistani Population. J Coll Physicians Surg Pak 2017; 27:414-418.